Immunogenicity of recombinant hepatitis B vaccine: comparison of two different vaccination schedules

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Immunogenicity of recombinant hepatitis B vaccine: comparison of two different vaccination schedules

BACKGROUND Neonatal immunization with hepatitis B (HB) vaccine induces protective levels of antibody (anti-HBs > or =10 IU/L) in a majority of vaccines. However, the duration of protection after HB vaccination in infants is unknown. A smaller proportion of children vaccinated beginning at birth with three doses of HB vaccine were found to have protective titers 5-10 years after initial vaccinat...

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Immunogenicity of two different hepatitis B vaccine schedules

A letter by Rashmi Ranjan Das et al. was recently published in Infection in which the authors commented on our article entitled ‘‘Immunogenicity of recombinant hepatitis B vaccine: comparison of two different vaccination schedules’’ [1]. We would like to take the opportunity provided by this letter to discuss our findings in particular and hepatitis B epidemiology in Turkey in general. The stud...

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Evaluation of Thimerosal Removal on Immunogenicity of Aluminum Salts Adjuvanted Recombinant Hepatitis B Vaccine

     Thimerosal, which is approximately 50% mercury by weight is a preservative widely used in vaccines since the 1930’s. It meets the requirements for a preservative as set forth by Pharmacopeia challenge test and has been shown to be effective against a broad spectrum of pathogens. In July 1999, the Public Health Service agencies and vaccine manufacturers agreed that thimerosal should be redu...

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Evaluation of Thimerosal Removal on Immunogenicity of Aluminum Salts Adjuvanted Recombinant Hepatitis B Vaccine

     Thimerosal, which is approximately 50% mercury by weight is a preservative widely used in vaccines since the 1930’s. It meets the requirements for a preservative as set forth by Pharmacopeia challenge test and has been shown to be effective against a broad spectrum of pathogens. In July 1999, the Public Health Service agencies and vaccine manufacturers agreed that thimerosal should be redu...

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Compliance and immunogenicity of two hepatitis B vaccination schedules in sex workers in Belgium.

OBJECTIVES To compare the coverage for the third dose and the compliance to two hepatitis B vaccination schedules: 0,1,4 versus 0,1,6 months, in commercial sex workers (CSW) in Belgium; to compare the immunogenicity of the actually administered schedules. METHODS In seven health centres in Belgium, hepatitis B vaccination was offered free of charge to CSW. In a randomised, prospective study a...

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ژورنال

عنوان ژورنال: Infection

سال: 2010

ISSN: 0300-8126,1439-0973

DOI: 10.1007/s15010-010-0031-2